as to minimize the effect of variability on precision in estimation and to reduce bias that may arise in hierarchical …

It is well-known that bias such as lead-time and length distort studies of screening efficacy whether survival or … incidence is of interest. A third bias, usually called overdiagnosis bias, occurs when an individual is only diagnosed with … disease before death from a different cause because he/she is screened. These forms of bias can also arise in observational …

bias preventive approach developed by Firth (1993) to handlethe bias of an estimator of the log-odds ratio parameter in … conditional logistic regression bysolving a modified score equation. The resultant estimator not only reduces bias but alsocan …