In an adaptive clinical trial research, it is common to use certain data-dependent design weights to assign individuals to treatments so that more study subjects are assigned to the better treatment. These design weights must also be used for consistent estimation of the treatment effects as...

In view of the cumbersome and often intractable numerical integrations required for a full likelihood analysis, several suggestions have been made recently for approximate inference in generalized linear mixed models (GLMMs). Two closely related approximate methods are the penalized...

We consider the elliptical distribution of n p-dimensional random vectors X1, ..., Xn having p.d.f. of the form k(n, p) [Lambda]-n/2 g([Sigma]j=1n(Xj-[theta])' [Lambda]-1(Xj-[theta])) as a generalization of the multivariate normal distribution. Let A denote the Wishart matrix defined by , where...

Forecasting for a time series of low counts, such as forecasting the number of patents to be awarded to an industry, is an important research topic in socio-economic sectors. Recently (2004), Freeland and McCabe introduced a Gaussian type stationary correlation model-based forecasting which...

We propose a dynamic logistic model for correlated non-stationary longitudinal binary responses collected from many independent individuals. We compute the correlations of the responses under the model and demonstrate that, unlike existing models, full ranges for the correlations are permitted.

It is well known that the ANOVA estimator of the random effects variance component in one-way random effects model can assume negative values. It is also well known that nonnegative quadratic unbiased estimators do not exist for estimating the random effects variance component (LaMotte, 1973)....