Quality-Adjusted Life Years (QALYs) estimate the utility derived from health states by taking account of life expectancy and quality of life. In applying QALYs to situations where health varies over time, it is usual to assume that we can add the utilities from constituent health states. This...

Quality-adjusted life year (QALY) models are widely used for economic evaluation in the health care sector. In the first part of the paper, we establish an overview of QALY models where health varies over time and provide a theoretical analysis of model identification and parameter estimation...

An important consideration when establishing priorities in health care is the likely effect that alternative allocations will have on the health-related quality of life (HRQoL) of the relevant population. This chapter considers some of the important issues surrounding the description and...