Under a random effects logistic regression model, asymptotic and exact test procedures in closed form for testing equality of binary responses are developed for comparing three treatments in a three-period crossover trial. Monte Carlo simulation is employed to evaluate the performance of these...

When assessing a treatment effect in the presence of confounders, we often employ stratified analysis and obtain a summary estimate of the risk difference (RD) under the assumption that the underlying RD is homogeneous across strata. In a randomized clinical trial (RCT), we may commonly come...

When comparing an experimental treatment with a standard treatment in a randomized clinical trial (RCT), we often use the risk difference (RD) to measure the efficacy of an experimental treatment. In this paper, we have developed four asymptotic interval estimators for the RD in a stratified RCT...