Manual of Mental Disorders, third and fourth editions (DSM-III/IV), with moderate-to-severe disease (Hamilton Depression … Rating Scale [HAMD] >=15 or Montgomery-Asberg Depression Rating Scale [MADRS] >=18), without co-morbidities or co …

treatment of depression. The availability of an effective armamentarium of antidepressant strategies, including venlafaxine, to …Worldwide, major depression is the leading cause of years lived with a disability, and the fourth cause of disability …-adjusted life years. Depression is second only to hypertension as the most common chronic condition encountered in general medical …

-effective alternative to amitriptyline and fluoxetine for the treatment of depression. Mirtazapine also has similar effects to SSRIs on … serotonin (5-hydroxytryptamine; 5-HT) reuptake inhibitors (SSRIs) on the basis of mean depression rating scale scores. Data from … than amitriptyline and placebo. Although differences were not statistically significant, mirtazapine had higher response …

frequencies of all medical services, and of services coded for depression, were compared between patients who received venlafaxine … higher for venlafaxine than TCA recipients ($US1948 vs $US1396) and mean costs not coded for depression were significantly … managed-care organisation of venlafaxine, a serotonin and norepinephrine reuptake inhibitor (SNRI), versus tricyclic …

) have become the primary form of pharmaceutical treatment for depression. As the patents of several top-selling SSRIs have …

Aim: To assess the relative cost effectiveness of escitalopram compared with venlafaxine XR in patients with major … clinical trial and examined the costs and quality of life of 251 patients taking escitalopram versus venlafaxine. Outpatients … fulfilling criteria for MDD were randomised to receive oral escitalopram 10-20 mg/day or venlafaxine 75-150 mg/day for 8 weeks …

, healthcare cost burden and productivity gains for patients successfully treated for depression. Most model-based studies …