, particularly indirect costs (e.g. lost productivity and absenteeism). The improved tolerability profile of fluoxetine and … of fluoxetine have mainly sought to determine whether its higher acquisition cost in comparison with tricyclic … direct healthcare costs for patients who start antidepressant therapy with fluoxetine are similar to, or lower than, those …

While fluoxetine is considerably more expensive than tricyclic antidepressants (TCAs), some previous studies have … suggested that general medical expenditures are lower among patients treated with fluoxetine. In this study, computerised …-care patients beginning antidepressant treatment with fluoxetine or one of 2 TCAs, imipramine or desipramine. Comparison was based …

depression, the evidence for fluoxetine and for the selective serotonin reuptake inhibitors in general suggest at best a modest …Fluoxetine continues to be remarkably successful; greater volumes of this drug are sold than for any other … fluoxetine, and highlight the response of the sponsor in the development of subsequent drugs for CNS disorders. …

Depression is a very costly chronic disease. An important cost driver is treatment failure caused by patient … medication switching contribute to the high cost of treatment. With the epidemiological data for depression demonstrating a rise … the treatment of depression. …

frequencies of all medical services, and of services coded for depression, were compared between patients who received venlafaxine …-care organisation. Patients and participants: Health plan members were included if they had a diagnosis of depression between July 1993 … costs coded for depression ($US451 vs $US311) and costs not coded for depression ($US4500 vs $US2090). Psychiatrists …

were illustrated using a Markov model of depression. Main outcome measures and results: The application of the refined …

compared the cost effectiveness of sertraline, citalopram, escitalopram and fluoxetine with paroxetine in elderly depressed … sertraline, citalopram, escitalopram or fluoxetine was more cost effective than paroxetine was 96.7%, 77.6%, 96.3% and 97 …) have become the primary form of pharmaceutical treatment for depression. As the patents of several top-selling SSRIs have …