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revascularisation procedure) avoided at 6 months in high risk patients undergoing coronary revascularisation treated with abciximab …: 62 abciximab-treated patients and 62 patients not treated with abciximab with high risk coronary lesions were matched … variability in the data. Results: At 6 months, abciximab-treated patients experienced an approximately 40% lower rate of ischaemic …
Persistent link: https://www.econbiz.de/10005590464
angioplasty (PCTA). PTCA could be administered with or without abciximab (a glycoprotein IIb/IIIa receptor antagonist), stent, or … stent plus abciximab (stent+). Results: CABG/stent alone has an incremental cost of more than Lstg 115 489 per additional … CABG/ stent would be added to abciximab (CABG/stent+) its incremental cost-effectiveness ratio would be Lstg 2529 per extra …
Persistent link: https://www.econbiz.de/10005449254
Objective: To examine the effect of abciximab treatment on intensive care length of stay for patients undergoing … abciximab was associated with a significantly shorter length of stay in intensive care compared with not administering a GPIIb … = 4793), administration of abciximab was also associated with a significantly shorter intensive care stay (0.27 fewer days; p …
Persistent link: https://www.econbiz.de/10005449044
Objective: To estimate the potential savings in overall cardiovascular disease (CVD) treatment costs for the US population with coronary artery disease (CAD) resulting from the use of amlodipine. Study design and methods: Using patient-level data from a retrospective analysis of the Prospective...
Persistent link: https://www.econbiz.de/10005449078
Background: In the Balloon Angioplasty and Anticoagulation Study (BAAS), coumarins added to routine aspirin therapy before coronary angioplasty reduced cardiac events at the cost of a slightly higher risk of bleeding complications. Objective: To determine the cost effectiveness of coumarin...
Persistent link: https://www.econbiz.de/10005449091
Objective: To evaluate the relationship between how much a new cardiovascular therapy improves clinical outcomes over current therapies and how much more it can cost while still remaining Design: We developed a decision model to predict the 6-month cumulative cost savings and increased life...
Persistent link: https://www.econbiz.de/10005449137
coronary syndromes. This analysis evaluates the economic impact of abciximab, a GP IIb/IIIa inhibitor, as an adjunct to … were randomised (2 : 5 ratio) to urokinase plus placebo or to urokinase plus abciximab. Economically relevant data were … more favourable for treatment with abciximab plus urokinase than for urokinase alone [9723 euros (EUR) vs EUR10 322; 2000 …
Persistent link: https://www.econbiz.de/10005243085
Abciximab is a monoclonal antibody fragment that inhibits platelet aggregation through antagonism of glycoprotein IIb … abciximab, as an adjunct to aspirin and heparin, to reduce by around one-third to one-half the incidence of ischaemic … risk, and abciximab also reduces complications in patients undergoing coronary stenting, although the drug does not appear …
Persistent link: https://www.econbiz.de/10005243110
Homocyst(e)ine, a sulphur-containing amino acid, is an intermediate formed during the metabolism of the essential amino acid methionine. Biological and epidemiological evidence suggest that elevated plasma levels of homocyst(e)ine are a risk factor for atherosclerosis and coronary heart disease...
Persistent link: https://www.econbiz.de/10005243072
Objective: To assess the economic impact of two polychemotherapy regimens for patients with advanced ovarian cancer from the perspective of the Belgian health insurance and financing system. Design: An economic evaluation was integrated in an intergroup randomised controlled trial (EORTC 55931)...
Persistent link: https://www.econbiz.de/10005243077