Objective: The choice of evidence used in decision modelling of healthcare interventions divides analysts into 2 groups: 1. those who favour randomised clinical trial (RCT) data; and 2. those who prefer `real world' data. This preference may have serious consequences if the end result is to...

Background: Nursing costs are poorly estimated in economic studies conducted in hospitals because of a lack of data on nursing times for day-to-day activities relating to patient care. Objective: To determine standard time values for nursing activities for specific indications in a cohort of...

Objective: The purpose of this study was to compare, from the payor perspective, the clinical and economic outcomes of olanzapine to those of haloperidol for the treatment of schizophrenia. Design and setting: Clinical, quality-of-life and resource utilisation data were prospectively collected...

Background:Background: Rasburicase is a recombinant urate-oxidase enzyme used to reduce high levels of plasma uric acid (PUA) resulting from tumour lysis syndrome (TLS). Rasburicase reduces PUA levels within 4 hours of administration, thereby minimizing the risk of serious complications from...

Background: Endophthalmitis is a severe condition that requires hospitalization with at least day care. Information on the incidence rate, costs and consequences of endophthalmitis is scarce. Objective: To estimate the number of patients with endophthalmitis hospitalized in France, as well as...

In this article we analyse how the costs of treating patients with HIV infection in the US have changed over time, with an emphasis on the relationship between inpatient hospitalization costs and the costs of highly active antiretroviral therapy (HAART). We examine how HIV treatment modes have...

Meropenem is a carbapenem antibiotic which is active against the majority of aerobic and anaerobic bacteria implicated in serious infections. Its therapeutic efficacy in a wide range of serious infections is similar to that of imipenem/cilastatin and standard combination drug regimens. Hence,...

Objective: To investigate whether the extent of systolic dysfunction is a useful predictor of the costs of healthcare and social support for patients with heart failure. Design: Cross-sectional study with collection of cost data attributed to management of heart failure in the previous year....