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Cost Analysis of 2 Empiric Antibacterial Regimens Containing Glycopeptides for the Treatment of Febrile Neutropenia in Patients with Acute Leukaemia

Bucaneve, Giampaolo; Menichetti, Francesco; Favero, … - In: PharmacoEconomics 15 (1999) 1, pp. 85-95

Objective: Patients with cancer-associated neutropenia are at high risk of developing severe infections which can be … fatal if treatment is not promptly administered. For this reason, fever is treated as soon as possible with broad spectrum …-containing antibacterial regimens for the treatment of febrile neutropenia in patients with acute leukaemia. Design and setting: A …

Persistent link: https://www.econbiz.de/10005449217

Meropenem: A Pharmacoeconomic Review of its Use in Serious Infections

Holliday, Stephen M.; Benfield, Paul - In: PharmacoEconomics 13 (1998) 3, pp. 359-377

Meropenem is a carbapenem antibiotic which is active against the majority of aerobic and anaerobic bacteria implicated …/cilastatin and standard combination drug regimens. Hence, meropenem is suitable for use as monotherapy. Although the acquisition cost … of meropenem is likely to be higher than that of aminoglycoside- and metronidazole-containing combination regimens, the …

Persistent link: https://www.econbiz.de/10005590296

Clinical and Economic Considerations of Empirical Antibacterial Therapy of Febrile Neutropenia in Cancer

Dranitsaris, George - In: PharmacoEconomics 16 (1999) 4, pp. 343-353

Febrile neutropenia is a condition that can develop in patients with cancer following the administration of … economic data on the empirical treatment of febrile neutropenia in patients with cancer. Therefore, there is a definite need to … combination of antibacterials or a single broad spectrum agent to offer extensive antibacterial coverage of both Gram-positive and …

Persistent link: https://www.econbiz.de/10004990335

Cost Effectiveness of Cephalosporin Monotherapy and Aminoglycoside/ Ureidopenicillin Combination Therapy: For the Treatment of Febrile Episodes in Neutropenic Patients

Paladino, Joseph A.; Fong, Debra A.; Forrest, Alan; … - In: PharmacoEconomics 18 (2000) 4, pp. 369-381

febrile episodes in adult patients with neutropenia enrolled in 5 randomised trials: 3 comparing monotherapy with ceftazidime …/ureidopenicillin combination therapy for the treatment of febrile episodes in adult patients with neutropenia. Design and setting: This was a … utilisation included costs for study antibacterials, treatment of adverse effects and failures, and hospitalisation. The primary …

Persistent link: https://www.econbiz.de/10005590555

Principles of Perioperative Antibacterial Prophylaxis: Management of Surgical Site Infections

Bohnen, John - In: Disease Management and Health Outcomes 6 (1999) 2, pp. 73-81

This article reviews perioperative antibacterial prophylaxis, a discrete in-hospital intervention that prevents surgical site infections and reduces the costs of complications and adverse effects of care. Clinical trials have shown that, when used appropriately, prophylactic antibacterial agents...

Persistent link: https://www.econbiz.de/10005448844

Management of Community-Acquired Pneumonia: The Role of Clarithromycin

Barman Balfour, Julia A.; Lamb, Harriet M. - In: Disease Management and Health Outcomes 6 (1999) 4, pp. 225-239

In patients with community-acquired pneumonia (CAP), it is uncommon for the causative pathogen to be identified when initial antimicrobial therapy is prescribed. Thus, an empirical approach is generally taken, based on antimicrobial therapy which covers the major pathogens of CAP. Although...

Persistent link: https://www.econbiz.de/10005448917

Selective Digestive Decontamination and its Use in Patients with Liver Disease

Ong, Janus; Younossi, Zobair M. - In: Disease Management and Health Outcomes 4 (1998) 1, pp. 17-26

intensive care units, in those who have multiple trauma or neutropenia and in bone marrow transplant recipients. SDD has been …

Persistent link: https://www.econbiz.de/10005448921

Cost Effectiveness of Ciprofloxacin plus Metronidazole versus Imipenem-Cilastatin in the Treatment of Intra-Abdominal Infections

Walters, Daniel J.; Solomkin, Joseph S.; Paladino, Joseph A. - In: PharmacoEconomics 16 (1999) 5, pp. 551-561

while continuing on active IV antibacterials; their success rate was 94%, mean duration of therapy was 10.1 days and mean …

Persistent link: https://www.econbiz.de/10005243176

Guidelines for the Prevention of Coronary Heart Disease: Relating Local Needs to Local Initiatives

Faergeman, Ole - In: Disease Management and Health Outcomes 4 (1998) 4, pp. 217-224

Coronary heart disease (CHD) emerged in North America and Europe as a leading cause of disease and death in the mid 20th century, and is now rapidly increasing in developing nations. By the mid 1980s, American and European academic institutions had issued several sets of guidelines indicating...

Persistent link: https://www.econbiz.de/10005243042

Incorporating Diabetes Care Into a Health Maintenance Organisation Setting: A Practical Guide

Davidson, Mayer B. - In: Disease Management and Health Outcomes 3 (1998) 2, pp. 71-80

This article describes 3 approaches to improving diabetes care in a health maintenance organisation (HMO) setting. The first approach was to identify which patients had not received a dilated eye examination in the past year, notify both them and their physician, and provide each with...

Persistent link: https://www.econbiz.de/10004990305

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