Background: Tablet splitting is used in pharmacy practice to adjust the dose to be administered. It is also being advocated as a method of reducing prescription drug costs. Methods: The potential for using this practice as a cost-saving method was examined. The top 200 prescription products in...

Objective: To calculate costs for the management of deep foot infections and to identify the most important factors related to treatment costs. Design: Costs for in-hospital care, surgery, investigations, antibacterials, visits to the foot-care team, orthopaedic appliances and topical treatment...

Background: The ongoing Type 1 Diabetes Prediction and Prevention Project in Finland (DIPP) is based on screening of genetic type 1 diabetes mellitus susceptibility, subsequent autoantibody follow-up and experimental preventive treatment with nasal insulin. Objective: To analyse direct costs of...

Idiopathic Parkinson's disease (PD) is a common chronic progressive neurodegenerative disorder associated with the progressive loss of dopaminergic neurons in the substantia nigra. The natural course of the disease may lead to severe disability despite a variety of pharmacological and surgical...

Objective: To determine the economic impact of an interventional programme aimed to increase the rate of clinical interventions undertaken in community pharmacy. Study design and perspective: A randomised controlled trial of 4 parallel groups of pharmacies, conducted from a government...

Objective: To estimate the economic impact of using tibolone 2.5mg compared with 17beta-estradiol 2mg/norethisterone acetate 1mg (E2/NETA) in postmenopausal women with climacteric symptoms. Design and setting: This was a modelling study performed from the perspective of the UK's National Health...

The available literature on cost benefit, cost effectiveness and cost utility of different drug and non-drug regimens in preventing hip fractures was reviewed. The cost of a hip fracture and of the different treatment regimens varied considerably from one country to another. In primary...

Objective: To use published data to compare the economic consequences of specific immunotherapy (SIT) lasting 3 years with those of continuous symptomatic treatment in patients with either pollen or mite allergy. Design and setting: The evaluation was conducted from the following 3 perspectives...

For practical reasons, in order to carry out economic evaluations of collective decisions, total costs will generally be compared with total benefits; hence, individuals' willingness to pay (WTP) or quality-adjusted life-years (QALYs) have to be estimated at an aggregate level. So far,...

Objective: To compare disease-related medical care and productivity costs, and utilities, in 482 patients with rheumatoid arthritis randomised to receive leflunomide, methotrexate or placebo during a 12-month period. Design and setting: Prospective pharmacoeconomic analysis of a 1-year...