eradication therapy using an omeprazole/amoxicillin/metronidazole regimen (or omeprazole/clarithromycin if allergic to penicillin …

/ clarithromycin and omeprazole or lansoprazole showed slightly lower eradication rates and were more costly. The eradication rates … omeprazole or ranitidine bismutrex showed the highest scores for eradication of H. pylori. The combinations amoxicillin … pharmacokinetics; drug interactions; resistance to antibacterials; efficacy; general adverse effects; complexity of the regimen …

-PAC(R) (lansoprazole 30mg, clarithromycin 500mg, amoxicillin 1g, all twice daily), relative to alternative pharmacological strategies in … (PPI)-clarithromycin-amoxicillin (PPI-CA), PPI-clarithromycin-metronidazole (PPI-CM), PPI-amoxicillin-metronidazole (PPI …

costs when compared with the other antibacterials. Low dosages of clarithromycin and azithromycin followed amoxicillin in …. Interventions: The antibacterials studied were amoxicillin, amoxicillin/clavulanate, azithromycin, cefaclor, cefuroxime axetil and … clarithromycin. Main outcome measures and results: The main outcome measured was the proportion of patients showing resolution or …

while continuing on active IV antibacterials; their success rate was 94%, mean duration of therapy was 10.1 days and mean …

(omeprazole, lansoprazole, pantoprazole and rabeprazole) are very similar, with any small differences in pharmacological … reflux oesophagitis also suggest similar efficacy for omeprazole and lansoprazole; data on pantoprazole and rabeprazole are … inclusion decisions. As a class, the PPIs are well tolerated. Minor drug interactions are reported for omeprazole, lansoprazole …

Objective: This 1-year study compared the cost effectiveness of omeprazole and ranitidine when used as initial therapy … the 3 treatment groups. Interventions: Patients were randomised to receive either omeprazole 20mg once daily, omeprazole … from ranitidine to omeprazole, and subsequently open maintenance treatment. Main outcome measures and results: The …

alternative therapy for penicillin-susceptible S. pneumoniae or M. catarrhalis infection. Clarithromycin has good in vitro … Legionella spp. Clarithromycin has similar efficacy to erythromycin in adults and children with mild to moderate CAP but is … encourage patient compliance. As with erythromycin, clarithromycin interacts with a wide range of drugs metabolised by the CYP …

children who do not respond to therapy. Based on pharmacokinetic and efficacy data, amoxicillin is recommended as first …-line treatment. Cefuroxime axetil, amoxicillin/clavulanic acid and ceftriaxone are recommended as second-line options. Conclusions … significantly better gastrointestinal tolerability than amoxicillin/clavulanic acid, another oral agent with a similar activity …