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An Economic Overview of Chronic Obstructive Pulmonary Disease

Ruchlin, Hirsch S.; Dasbach, Erik J. - In: PharmacoEconomics 19 (2001) 6, pp. 623-642

Chronic obstructive pulmonary disease (COPD) is a major cause of mortality and morbidity. Relatively few pharmacoeconomic studies have been conducted on this disease. This article reviews available information about the utilisation of healthcare resources and cost of care, and the cost or cost...

Persistent link: https://www.econbiz.de/10005243194

Applying Epidemiology-Based Outcomes Research to Clinical Decision-Making: A Hypothetical Model of Biotechnology Therapy in Gram-Negative Sepsis

Wang, Edward C.Y.; Grasela, Thaddeus H.; Walawander, … - In: PharmacoEconomics 15 (1999) 4, pp. 385-393

Objective: Sepsis occurs in a heterogeneous population. A prospective nationwide surveillance study found that populations stratified by infection type had significant differences in the incidence of sepsis syndrome, rate of complications and mortality. The objective of this study was to explore...

Persistent link: https://www.econbiz.de/10004990322

Community-Acquired Pneumonia and its Management: The Role of Levofloxacin

Perry, Caroline M.; Goa, Karen L. - In: Disease Management and Health Outcomes 9 (2001) 1, pp. 43-64

azithromycin plus ceftriaxone and similar in efficacy to both amoxicillin/clavulanic acid and gatifloxacin. Data comparing the … ceftriaxone and was more cost effective than cefuroxime plus erythromycin, or ceftriaxone or ciprofloxacin. Conclusions …

Persistent link: https://www.econbiz.de/10005448775

Acute Exacerbations of Chronic Bronchitis: A Pharmacoeconomic Review of Antibacterial Use

Morris, Stephen; Anderson, Pippa; Irwin, Debra E. - In: PharmacoEconomics 20 (2002) 3, pp. 153-168

antibacterials in the management of ABECB, and the factors that may affect the cost-effectiveness of antibacterials in the management … follows: 1. a key factor affecting the cost-effective use of antibacterials in the management of ABECB is the definitive … ensuring that antibacterials are not prescribed unnecessarily; 2. current evidence suggests but does not prove that use of more …

Persistent link: https://www.econbiz.de/10005449055

Should Antibacterials Be Deregulated?

Rovira, Joan; Figueras, Montserrat; Segu, Josep L. - In: PharmacoEconomics 13 (1998) 5, pp. 499-508

Deregulation of antibacterials is a recurrent topic in the debate on pharmaceutical policy. This article focuses on one … aspect of pharmaceutical regulation, namely the requirement of a medical prescription for purchasing antibacterials. However …

Persistent link: https://www.econbiz.de/10005449163

Cost Analysis of 2 Empiric Antibacterial Regimens Containing Glycopeptides for the Treatment of Febrile Neutropenia in Patients with Acute Leukaemia

Bucaneve, Giampaolo; Menichetti, Francesco; Favero, … - In: PharmacoEconomics 15 (1999) 1, pp. 85-95

Objective: Patients with cancer-associated neutropenia are at high risk of developing severe infections which can be fatal if treatment is not promptly administered. For this reason, fever is treated as soon as possible with broad spectrum antibacterial therapy. The objective of this study was...

Persistent link: https://www.econbiz.de/10005449217

Cost Efficacy of Tazobactam/Piperacillin versus Imipenem/Cilastatin in the Treatment of Intra-Abdominal Infection

Dietrich, Eva Susanne; Schubert, Bjorn; Ebner, Winfried; … - In: PharmacoEconomics 19 (2001) 1, pp. 79-94

Objective: To compare the cost, efficacy and cost efficacy of tazobactam/ piperacillin and imipenem/cilastatin in the treatment of intra-abdominal infection. Design: The analysis was retrospective and based on a decision tree. Effectiveness data were obtained from 19 published clinical trials....

Persistent link: https://www.econbiz.de/10005449220

Management of Acute Otitis Media: Defining the Role of Cefuroxime Axetil

Lamb, Harriet M.; Spencer, Caroline M. - In: Disease Management and Health Outcomes 8 (2000) 6, pp. 337-353

Growing concern about the rapid emergence of penicillin-resistant Streptococcus pneumoniae, as well as beta-lactamase-mediated resistance among Haemophilus influenzae and Moraxella catarrhalis, has lead to reconsideration of the management of acute otitis media in children. Acute otitis media is...

Persistent link: https://www.econbiz.de/10005404604

Antibacterials and Acute Exacerbation of Chronic Bronchitis: Issues for Formulary Decision Makers

Chock, Alan; Gong, Vera; Destache, Christopher J. - In: Disease Management and Health Outcomes 10 (2002) 6, pp. 333-336

The utility of antibacterials in the management of acute exacerbations of chronic bronchitis (AECB) and the related …

Persistent link: https://www.econbiz.de/10005404640

Threshold Analysis of Helicobacter pylori Therapy

Sonnenberg, Amnon - In: PharmacoEconomics 14 (1998) 4, pp. 423-432

Objective: Conflicting recommendations have been made on whom to treat with antibacterials to eradicate Helicobacter … choosing one type of therapy over another, a trial of antibacterials appears indicated irrespective of any firm validation of H …

Persistent link: https://www.econbiz.de/10005404790