Showing 1 - 10 of 35,986
, in periods or patients with elevated risk, more intensive treatment with clopidogrel (alone or together with aspirin) is … compared with aspirin alone and, based on an indirect comparison, also when compared with clopidogrel. Conclusions: The cost … 5 years), and clopidogrel for the treatment of symptomatic cardiovascular disease or acute coronary syndrome (for a …
Persistent link: https://www.econbiz.de/10005404994
unstable angina (UA). The CURE (Clopidogrel in Unstable angina to prevent Recurrent Events) trial has shown that clopidogrel …:Objective: To evaluate the cost effectiveness of 1 year of treatment with clopidogrel in addition to aspirin in NSTEMI or UA … aspirin treatment group and 8.41 years in the aspirin plus clopidogrel treatment group. The corresponding discounted QALYs …
Persistent link: https://www.econbiz.de/10010552619
acetylsalicylic acid (aspirin) and clopidogrel have been shown to reduce the risk of recurrent cardiovascular events in various … subgroups of patients with vascular disease. Objective: To estimate the cost effectiveness of clopidogrel versus aspirin in …. Methods: A Markov model combining clinical, epidemiological and cost data was used to assess the economic value of clopidogrel …
Persistent link: https://www.econbiz.de/10008462721
adverse cardiac events with clopidogrel, but not with prasugrel. The frequency of the *2 allele varies by ethnicity and … patients with generic clopidogrel compared with prasugrel, and also compared with the genetically guided strategy that *2 … allele carriers receive prasugrel and non-carriers receive clopidogrel. Abstract: Methods:Methods: A decision-tree model …
Persistent link: https://www.econbiz.de/10010579443
efficacy in the secondary prevention of atherothrombotic events. Although clopidogrel seems to be superior to aspirin in terms …. Abstract: Objective:Objective: The aim of this study was to conduct a cost-effectiveness analysis comparing clopidogrel with … rates reported in the CAPRIE trial. The effect of clopidogrel was applied only during the first 2 years of the model …
Persistent link: https://www.econbiz.de/10010567015
Introduction: This analysis compared the cost effectiveness of adding ezetimibe to atorvastatin therapy versus atorvastatin titration or adding cholestyramine (a resin) for patients at high risk of a coronary artery disease (CAD) event who did not reach target cholesterol levels on their current...
Persistent link: https://www.econbiz.de/10005449107
Objective: The CARDS trial, a multicentre, randomized, controlled trial, found that atorvastatin 10 mg/day for patients with type 2 diabetes mellitus and normal low-density lipoprotein (LDL)-cholesterol significantly reduced cardiovascular (CV) events, including stroke. We estimated the cost...
Persistent link: https://www.econbiz.de/10005449278
aspirin arm of the CAPRIE (Clopidogrel versus Aspirin in Patients at Risk of Ischaemic Events) study. Direct costs from the …
Persistent link: https://www.econbiz.de/10005404854
Clopidogrel (Plavix(R)) is a selective inhibitor of adenosine diphosphate-induced platelet aggregation. In patients … with acute coronary syndromes (ACS) [unstable angina or non-ST-segment elevation myocardial infarction], clopidogrel plus … plus aspirin in the well designed clinical trial CURE (Clopidogrel in Unstable angina to prevent Recurrent Events) and its …
Persistent link: https://www.econbiz.de/10005590293
Background: Low-dose acetylsalicylic acid (ASA; 75-325 mg) is a mainstay of therapy for patients at high risk of cardiovascular (CV) events. However, in some patients, such treatment is associated with upper gastrointestinal (GI) adverse effects, e.g. dyspeptic symptoms, peptic ulceration, and...
Persistent link: https://www.econbiz.de/10011005087