Showing 1 - 10 of 537
Modern genetics studies require the use of many specialty software programs for various aspects of the statistical …) exporting the haplotype/single nucleotide polymorphism data from Stata to Haploview. Copyright 2010 by StataCorp LP. …
Persistent link: https://www.econbiz.de/10008677214
Persistent link: https://www.econbiz.de/10010924834
Persistent link: https://www.econbiz.de/10010608767
This data spotlight examines availability and enrollment trends for Medicare Advantage Special Needs Plans, which provide a managed care option for beneficiaries with significant or relatively specialized care needs. These plans account for a small share of Medicare enrollment today, but are...
Persistent link: https://www.econbiz.de/10010609660
Persistent link: https://www.econbiz.de/10008596120
Characterizing the genetic correlates to complex diseases requires consideration of a large number of potentially informative biological markers. In addition, attention to alignment of alleles within or across chromosomal pairs, commonly referred to as phase, may be essential for uncovering true...
Persistent link: https://www.econbiz.de/10005752620
recently suggested models of haplotype block structure. We propose to apply the new LD measure to define haplotype blocks … proposed method integrates information on the two main existing criteria in defining haplotype blocks, namely, LD and haplotype …
Persistent link: https://www.econbiz.de/10005584916
``disease haplotype'' leads to the increased risk, attention focusses on the relative risks associated with a single copy, or … two copies of the disease haplotype, relative to individuals with no copies. In this setting, case frequencies of the … haplotype pairs are in Hardy-Weinberg Equilibrium (HWE) only if the combined influence of the two copies of the disease …
Persistent link: https://www.econbiz.de/10005585096
disease-haplotype association using unphased genotype data is essentially a problem of handling a missing covariate in a case …-control design. There are several methods for estimating a disease-haplotype association parameter in a matched case-control study …. Here we propose a conditional likelihood approach for inference regarding the disease-haplotype association using unphased …
Persistent link: https://www.econbiz.de/10005585153
Understanding the genetic underpinnings to complex diseases requires consideration of sophisticated analytical methods designed to uncover intricate associations across multiple predictor variables. At the same time, knowledge of whether single nucleotide polymorphisms within a gene are on the...
Persistent link: https://www.econbiz.de/10005585156