Genetic testing has long been part of Canada’s health system, but the scope of genetic testing is growing into new areas. Whereas traditional tests predominantly foretell the health of future generations, new tests increasingly tell individuals about their own health and risks. And whereas...

Objective: The objectives of this study were 1. to develop a conceptual framework for selecting hospitals for unit cost estimates in national and international multicentre trials and 2. to test the impact of alternative hospital selection on the cost results. Design and setting: Within the...

Background: The positive results of a randomised clinical trial of rivastigmine in patients with dementia associated with Parkinson's disease have been published recently. Patient-level healthcare utilisation data were also collected, and this report is the economic evaluation based on these...

Objective: To assess the cost effectiveness of a multidrug prepackaged regimen for Helicobacter pylori, the Hp-PAC(R) (lansoprazole 30mg, clarithromycin 500mg, amoxicillin 1g, all twice daily), relative to alternative pharmacological strategies in the management of confirmed duodenal ulcer over...

When choosing between mutually exclusive treatment options, it is common to construct a cost-effectiveness frontier on the cost-effectiveness plane that represents efficient points from among the treatment choices. Treatment options internal to the frontier are considered inefficient and are...

Much of the justification for environmental rulemaking rests on estimates of the benefits to society of reduced mortality rates. This research aims to fill gaps in the literature that estimates the value of a statistical life (VSL) by designing and implementing a contingent valuation study for...

Osteoporosis is a major cause of morbidity, mortality and resource cost amongst the elderly population. Hip fracture is the most serious of the osteoporotic fractures, with approximately 10-20% of patients dying within six months of sustaining a fracture. Furthermore, hip fractures are the most...