Showing 1 - 10 of 47,982
for 4 PEP strategies: the current USPHS recommendations, triple drug therapy, zidovudine monotherapy or no prophylaxis. A …
Persistent link: https://www.econbiz.de/10005449098
disease. Results of a pivotal randomised study (DMP 266-006) comparing efavirenz- versus indinavir-based triple combination … with the indinavir-based regimen. In conclusion, current treatment guidelines for HIV infection recognise efavirenz … greater virological response to efavirenz- than indinavir-based triple combination therapy, and the efavirenz-based regimen …
Persistent link: https://www.econbiz.de/10005590353
Objective: The aim of the study was to measure the use and estimate the cost of HIV service provision in England. Design and Setting: Standardised activity and case-severity data were collected prospectively in 10 English HIV clinics (5 London and 5 non-London sites) for the periods 1 January...
Persistent link: https://www.econbiz.de/10005449215
The advent of highly active antiretroviral therapy (HAART), including protease inhibitors and/or non-nucleoside reverse transcriptase inhibitors, for the treatment of HIV infection has led to a dramatic decline of morbidity and mortality. The acquisition costs of HAART are substantial. However,...
Persistent link: https://www.econbiz.de/10005243093
indinavir and 2 nucleoside reverse transcriptase inhibitors (NRTIs; zidovudine and lamivudine) in HIV-positive patients. Design … dollars (1998 values) relative to initial therapy with the indinavir-containing regimen. Patients who receive efavirenz are …Objective: To compare the clinical and economic outcomes associated with triple therapy containing efavirenz or …
Persistent link: https://www.econbiz.de/10005590510
developed countries. Two nucleoside analogue reverse transcriptase inhibitors, such as lamivudine and zidovudine, plus a … for initial or second-line treatment. A combination formulation of lamivudine and zidovudine has recently become available …. Combination therapy with lamivudine and zidovudine (as dual therapy or in combination with another nucleoside analogue reverse …
Persistent link: https://www.econbiz.de/10005404625
lamivudine + (zidovudine or didanosine or zalcitabine or stavudine)]; and ERA-III [2 nucleoside reverse transcriptase inhibitors …) regimens, denoted as ERA-I [zidovudine + (didanosine or zalcitabine)]; ERA-II [stavudine + (didanosine or zalcitabine) or …
Persistent link: https://www.econbiz.de/10005449111
carcinoma. Lamivudine is the only oral antiviral agent approved for the treatment of patients with chronic hepatitis B …. Lamivudine is useful in a wide range of patients with chronic hepatitis B and ongoing viral replication. In patients with … compensated liver disease treated for 52 weeks in multicenter randomized, double-blind clinical studies, lamivudine 100 mg …
Persistent link: https://www.econbiz.de/10005590196
As care for HIV/AIDS becomes more concentrated within specific providers and organisations, it would be useful to have indicators to describe the quality of care. This paper reviews concepts related to quality of care, and practical issues including sampling and risk adjustment. Indicators can...
Persistent link: https://www.econbiz.de/10005590112
Objective: To describe the use of hospital and community services for children infected with HIV and estimate the cost per patient-year by stage of HIV infection during the era of antiretroviral monotherapy. Design: Data on the use of hospital services were collected from case notes; the use of...
Persistent link: https://www.econbiz.de/10005449015