Lourenço da Silva, A.; Marc, A.; Engasser, J.M.; … - In: Mathematics and Computers in Simulation (MATCOM) 42 (1996) 2, pp. 197-205
A methodology is proposed to evaluate which components of the culture medium limit the growth of mammalian cells during the culture. It is based on a kinetic model that describes the hybridoma growth decreasing and death enhancing effects of glucose, amino-acids, serum and oxygen depletion, on...