Randomised controlled trials (RCTs) are a major source of individual patient level data (IPD) on the clinical outcomes, costs and other measures of health consequences associated with alternative healthcare interventions. These data are typically used to establish the ‘value for...

Background: Reducing rates of healthcare acquired infection has been identified by the Australian Commission on Safety and Quality in Health Care as a national priority. One of the goals is the prevention of central venous catheter-related bloodstream infection (CR-BSI). At least 3,500 cases of...

Maternal and infant mortality is a global health issue with a significant social and economic impact. Each year, over half a million women worldwide die due to complications related to pregnancy or childbirth, four million infants die in the first 28 days of life, and eight million infants die...

This article presents the cost-effectiveness results of a randomised controlled trial conducted in two Australian cities. The trial was designed to assess the safety, efficacy and cost-effectiveness of buprenorphine versus methadone in the management of opioid dependence. The trial Utilised a...

Introduction: Health care costs are on the rise in Australia and rational decisions are necessary to prioritise interventions for the allocation of limited resources. As new vaccines are being introduced, budgetary allocations for immunisation are increasing. Economic analyses are useful in...

Background The costs of healthcare are on the rise. With an ageing population, growing demand for health services and expensive new technologies, Australia’s annual health care bill has more than doubled in the last ten years, and is projected to increase a further 127% by 2033. As third-party...

Background: Evidence suggests benefits of orthogeriatric co-management (OGCM) for hip fracture patients. Yet, evidence on cost-effectiveness is limited and based on small datasets. The aim of our study was to conduct an economic evaluation of the German OGCM for geriatric hip fracture patients....

Objectives: To estimate the cost savings and health benefits in the UK NHS that could be achieved if human milk usage in the NICU was increased. Methods: A systematic review established the disease areas with the strong sources of evidence of the short, medium and long-term benefits of human...