A population that can be joined at a known sequence of discrete times is sampled cross-sectionally, and the sojourn times of individuals in the sample are observed. It is well known that cross-sectioning leads to length-bias, but less well known that it may result also in dependence among the...

Phase I clinical trials are conducted in order to find the maximum tolerated dose (MTD) of a given drug from a finite set of doses. For ethical reasons, these studies are usually sequential, treating patients or group of patients with the best available dose according to the current knowledge....

We consider the classical problem of selecting the best of two treatments in clinical trials with binary response. The target is to find the design that maximizes the power of the relevant test. Many papers use a normal approximation to the power function and claim that Neyman allocation that...

Statistical models in econometrics, biology, and most other areas, are not expected to be correct, and often are not very accurate. The choice of a model for the analysis of data depends on the purpose of the analysis, the relation between the data and the model, and also on the sample or data...

We study a class of optimal allocation problems, including the well-known Bomber Problem, with the following common probabilistic structure. An aircraft equipped with an amount x of ammunition is intercepted by enemy airplanes arriving according to a homogenous Poisson process over a fixed time...