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. Threshold values of returns to scale and the recombination probability define regions where either specialization or diversity …
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organizations literature. Recent writings have tended to offer modularity as, at least, a partial solution to this design problem …. Two unifying themes characterize the extant literature on modularity. The first addresses the contingencies under which … modularity wherein the focus is on the advantages that modular design structures have over their integrated counterparts. However …
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Exaptation, the cooption of existing technologies for emergent functions, is an important but neglected mechanism for innovation. Exaptation may enable an existing technology to (a) construct a new technological niche, (b) enter into a preexisting niche, or (c) transform the internal...
Persistent link: https://www.econbiz.de/10010930888
Most findings from genome-wide association studies (GWAS) are consistent with a simple disease model at a singel nucleotide polymorphism, in which each additional copy of the risk allele increases risk by the same multiplicative factor, in contrast to dominance or interaction effects. As others...
Persistent link: https://www.econbiz.de/10009441573
In this study, we define a chi-square random field on a multi-dimensional lattice points index set with a direct product covariance structure and consider the distribution of the maximum of this random field. We provide two approximate formulas for the upper tail probability of the distribution...
Persistent link: https://www.econbiz.de/10011000058
Redundant gene functions are ubiquitous, and they are a potentially important source of evolutionary innovations on the biochemical level. It is therefore highly desirable to understand the mechanisms governing their evolution. Gene duplication is clearly a prominent mechanism generating...
Persistent link: https://www.econbiz.de/10005790837
A number of new techniques for reliability improvement and risk reduction based on the inversion method, such as … the first time. By using detailed calculations, it has been demonstrated how the new technique ‘repeated inversion … variable speeds. It has been demonstrated that for pressure vessels, an inversion of the geometric parameters by maintaining an …
Persistent link: https://www.econbiz.de/10012047263