This paper is a case study of the transformation in research methods which occurred in a large U.S. pharmaceutical firm as a result of the biotech revolution. This transformation is inconsistent with the hypothesis that technological revolutions make existing firms obsolete and consistent with...

The local academic science base plays a dominant role in determining where and when biotechnology is adopted by existing firms or -- much more frequently -- exploited by new entrants in the U.S. In Japan this new dominant technology has almost exclusively been introduced through organizational...

"This paper extends the concept of star scientist to all areas of science and technology. We follow 1,838 stars' careers 1981-2004, using their publication history to locate them each year. The number of stars in a U.S. region or in one of the top-25 science and technology countries has a...