In microarray experiments quality often varies, for example between samples and between arrays. The need for quality control is therefore strong. A statistical model and a corresponding analysis method is suggested for experiments with pairing, including designs with individuals observed before...

Statistical models for spot shapes and signal intensities are used in image analysis of laser scans of microarrays. Most models have essentially been based on the assumption of independent pixel intensity values, but models that allow for spatial correlation among neighbouring pixels can...

Clumping of gene properties like expression or mutant phenotypes along chromosomes is commonly detected using completely random null-models where their location is equally likely across the chromosomes. Interpretation of statistical tests based on these assumptions may be misleading if...