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An objective of microarray data analysis is to identify gene expressions that are associated with a disease related outcome. For each gene, a test statistic is computed to determine if an association exists, and this statistic generates a marginal p-value. In an effort to pool this information...
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Testing the equality of two survival distributions can be difficult in a prevalent cohort study when non-random sampling of subjects is involved. Owing to the biased sampling scheme, the independent censoring assumption is often violated. Although the issues about biased inference caused by...
Persistent link: https://www.econbiz.de/10008670657
In some assays, a diluted suspension of infected cells is plated onto multiple wells. In each well the number of genome copies of virus, "Y", is recorded, but interest focuses on the number of infected cells, "X", and the number of genome copies in the infected cells, "W"<sub>1</sub>,…,"W"<sub>"X"</sub>. The...
Persistent link: https://www.econbiz.de/10008671158
Model misspecification can be a concern for high-dimensional data. Nonparametric regression obviates model specification but is impeded by the curse of dimensionality. This paper focuses on the estimation of the marginal mean response when there is missingness in the response and multiple...
Persistent link: https://www.econbiz.de/10008675548
type="main" xml:id="rssc12051-abs-0001" <title type="main">Summary</title> <p>In recent decades there has been an increase in the reported incidence of clinical pertussis in many countries. Estimation of the true circulation of the bacterium Bordetella pertussis is most reliably made on the basis of studies that measure...</p>
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