We consider a generalization of the classical quadratic assignment problem, where material flows between facilities are uncertain, and belong to a budgeted uncertainty set. The objective is to find a robust solution under all possible scenarios in the given uncertainty set. We present an exact...

Facility layout problems involve the location of facilities in a planar arrangement such that facilities that are strongly connected to one another are close to each other and facilities that are not connected may be far from one another. Pairs of facilities that have a negative connection...

Pareto Local Search (PLS) is a simple and effective local search method for tackling multi-objective combinatorial optimization problems. It is also a crucial component of many state-of-the-art algorithms for such problems. However, PLS may be not very effective when terminated before...

In this paper we investigate the problem of locating medications in automated dispensing cabinets (ADCs) to minimize human selection errors. We formulate the multiple-drawer medication layout problem and show that the problem can be formulated as a quadratic assignment problem. As a way to...

Since procedures for producing optimal solutions to a quadratic assignment problem are computationally infeasible for any but small problems, heuristic techniques for producing approximate solutions must be employed for the solution of real practical problems. This paper presents the results of...