The term "epistasis" is sometimes used to describe some form of statistical interaction between genetic factors and is alternatively sometimes used to describe instances in which the effect of a particular genetic variant is masked by a variant at another locus. In general statistical tests for...

A number of results concerning attributable fractions for sufficient cause interactions are given. Results are given both for etiologic fractions (i.e. the proportion of the disease due to a particular sufficient cause) and for excess fractions (i.e. the proportion of disease that could be...

Various assumptions have been used in the literature to identify natural direct and indirect effects in mediation analysis. These effects are of interest because they allow for effect decomposition of a total effect into a direct and indirect effect even in the presence of interactions or...