The proliferation of many clinical studies obtaining multiple biophysical signals from several individuals repeatedly in time is increasingly recognized, a recognition generating growth in statistical models that analyze cross-sectional time series data. In general, these statistical models try...

The main concern of financial time series analysis is how to forecast future values of financialvariables, based on all available information. One of the special features of financial variables,such as stock prices and exchange rates, is that they show changes in volatility, or variance,over...

In older adults, maintaining balance and processing information typically interfere with each other, suggesting that executive functions may be engaged for both. We investigated associations between measures of inhibitory processes and standing postural control in healthy young and older adults....

A laboratory study of older adults with osteoarthritis and their spouses was conducted to examine the unique influence of exposure to suffering on caregivers' risk for impaired psychological and physical health. Spouses' blood pressure (BP) and heart rate (HR) were monitored during 2 tasks...

This paper explores some of the problems associated with traditional canonical correlation. A response surface methodology is developed to examine the stability of the derived linear functions, where one wishes to investigate how much the coefficients can change and still be in an e-neighborhood...

In many maintenance treatment trials, patients are first enrolled into an open treatmentbefore they are randomized into treatment groups. During this period, patients are followedover time with their responses measured longitudinally. This design is very common intoday's public health studies of...

The Generalized Additive model (GAM) has been used as a standard tool for epidemiologic analysis exploring the effect of air pollution on population health during the last decade as it allows nonparametric relationships between the independent predictors and response. One major concern to the...

Generalized additive model (GAM) with natural cubic splines (NS) has been commonly used as a standard analytical tool in time series studies of health effects of air pollution. Standard model selection procedures used in GAM ignore the uncertainty in model fitting. This may lead to biased...