To overcome the problem of insufficient research and development (R&D) on vaccines for diseases concentrated in low-income countries, sponsors could commit to purchase viable vaccines if and when they are developed. One or more sponsors would commit to a minimum price that would be paid per...

Comparative effectiveness research (CER) has assumed an increasing role in drug coverage and, in some cases, pricing decisions in Europe, as decision-makers seek to obtain better value for money. This issue brief comparatively examines the use of CER across six countries—Denmark, England,...

The aim of this paper is to estimate the return to the UK from health sector R&D drawing on the value of life methodology and the work by Murphy and Topel (2003). While acknowledging the caveats arising in making such calculations, not least the lack of consideration given to spillover effects...

The economic impact of serious conditions such as schizophrenia is felt widely. The impact on overall health care budgets can be as much as 3% of the total, but there are also other costs, especially those associated with lost productivity, as typically only about one-fifth of all people with...

We demonstrate a method for integrating environmental effects into a computable general equilibrium model. This is a critical step forward toward the development of improved integrated assessment models of environmental change. We apply the method to examine the economic consequences of air...

Aim: To assess the impact of early intervention (EI) services on service costs for people with first-episode psychosis. Methods: A decision model was constructed to map the care pathways following input from EI services and from standard care. A Markov process was used to run the model over 18...

Background: High rates of health needs among adults with intellectual disabilities flag the need for information about the economic consequences of strategies to identify and address unmet needs. Health-check interventions are one such strategy, and have been demonstrated to effect health gains...

Objective: To examine whether several biomarkers of endothelial function and inflammation improve prediction of type 2 diabetes over 5.9 years of follow-up, independent of traditional risk factors. Methods and Procedures: A total of 1,455 participants from the Western New York Study, free of...

Despite a large volume of research, understanding the influences on general practitioner referral behaviour remains limited. This paper argues for the value of an approach to this area based on the analysis of individual referral decisions, rather than aggregated referral statistics. A framework...

Purpose – This paper aims to report on research into human resource management within an operations management environment; specifically, operational team-work amongst health care workers in a hospital. Design/methodology/approach – Eight operational teams within a UK National Health...