Rationale: The minimally important difference (MID) represents the smallest change on a patient reported outcome which can be considered important. Currently, only Walters and Brazier (2005) have published MID data for health utilities. Their results suggested that the MID preference-based...

Increasing drug costs in the US have prompted employers and insurers alike to turn to higher drug copays for cost containment. The effect of rising copays on compliance with statins (HMG-CoA reductase inhibitors) treatment has received surprisingly little attention in the applied literature....