In clinical practice, red blood cells (RBCs) have a maximal shelf life (MSL) of 42 days. Recent studies suggest managing RBC inventory with a more restrictive MSL. To this end, a new simulation optimization (SO) framework is proposed for blood supply chain inventory management with ABO blood...

A simulation optimization framework is proposed for supply chain inventory management of highly perishable products. A new replenishment policy based on old inventory ratio is developed, hence called OIR policy. It is an age-based policy using only partial age information to measure the...

In this paper, the optimal replenishment policies of capacitated supply chains (SC) operating under two different control strategies (decentralized vs. centralized) and various demands are determined and insights useful to management are discussed. The details of the system used, including the...