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Population toxicokinetics of ethylene: Models and validation of first order assumptions on kinetic processes
Selinski, Silvia; Quinke, Barbara; Golka, Klaus; Bolt, … - Institut für Wirtschafts- und Sozialstatistik, … - 2002
basic petrochemical industrial compounds, ethylene 2 (ethene), which is also a physiological body constituent, to its … metabolite, ethylene oxide, which is a proven carcinogen. …
Persistent link: https://www.econbiz.de/10010955501
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Population toxicokinetics of ethylene : models and validation of first order assumptions on kinetic processes
Selinski, Silvia; Quinke, Barbara; Golka, Klaus; Bolt, … - 2002
basic petrochemical industrial compounds, ethylene 2 (ethene), which is also a physiological body constituent, to its … metabolite, ethylene oxide, which is a proven carcinogen. …
Persistent link: https://www.econbiz.de/10009770916
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Estimation of toxicokinetic population parameters in a four-stage hierarchical model
Selinski, Silvia - Institut für Wirtschafts- und Sozialstatistik, … - 2000
A basic part in the risk assessment of potential carcinogens is the determination of toxicokinetic parameters. The partition of the xenobiotic in the body of experimental animals is a first step of the biochemical pathway of the formation of DNA adducts which might lead to the development of...
Persistent link: https://www.econbiz.de/10010955416
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Interindividual and interoccasion variability of toxicokinetic parameters of uptake, exhalation, and metabolism of ethylene
Schirm, Florian A.; Selinski, Silvia - Institut für Wirtschafts- und Sozialstatistik, … - 2000
the results of an inhalation study with one of the basic petrochemical industrial compounds, ethylene (ethene). Two …
Persistent link: https://www.econbiz.de/10010955473
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Interindividual and interoccasion variability of toxicokinetic parameters of uptake, exhalation, and metabolism of ethylene
Schirm, Florian A.; Selinski, Silvia - 2000
the results of an inhalation study with one of the basic petrochemical industrial compounds, ethylene (ethene). Two …
Persistent link: https://www.econbiz.de/10010316508
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Estimation of toxicokinetic population parameters in a four-stage hierarchical model
Selinski, Silvia - 2000
A basic part in the risk assessment of potential carcinogens is the determination of toxicokinetic parameters. The partition of the xenobiotic in the body of experimental animals is a first step of the biochemical pathway of the formation of DNA adducts which might lead to the development of...
Persistent link: https://www.econbiz.de/10010316653
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Estimation of toxicokinetic population parameters in a four-stage hierarchical model
Selinski, Silvia - 2000
A basic part in the risk assessment of potential carcinogens is the determination of toxicokinetic parameters. The partition of the xenobiotic in the body of experimental animals is a first step of the biochemical pathway of the formation of DNA adducts which might lead to the development of...
Persistent link: https://www.econbiz.de/10009789899
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Interindividual and interoccasion variability of toxicokinetic parameters of uptake, exhalation, and metabolism of ethylene
Schirm, Florian A.; Selinski, Silvia - 2000
the results of an inhalation study with one of the basic petrochemical industrial compounds, ethylene (ethene). Two …
Persistent link: https://www.econbiz.de/10009787268
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Outlier detection in experimental data using a modified Hampel identifier
Selinski, Silvia; Becker, Claudia - Institut für Wirtschafts- und Sozialstatistik, … - 2001
ethylene (ethene). This study was designed to determine the individual and population parameters, i. e. the parameters which … variability of the processes of inhalation, exhalation, and metabolic elimination of the chemical ethylene in male Sprague- Dawley …
Persistent link: https://www.econbiz.de/10010955362
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Interindividual and interoccasion variability of toxicokinetic parameters in population models
Selinski, Silvia; Urfer, Wolfgang - Institut für Wirtschafts- und Sozialstatistik, … - 1998
part of a strategy to determinate the processes of uptake, elimination, and metabolism of the gas ethylene, which is a …
Persistent link: https://www.econbiz.de/10010955364