In this paper, we have presented the second level nesting of Bonney's disposition model (Bonney, 1998) and examined the implications of higher level nesting of the disposition model in relation to the dimension of the parameter space. We have also compared the performance of the disposition...

In the present study we investigate the data provided by the karstwater level monitoring system set up in the Transdanubian Mountains, more precisely in the Bakony, the Keszthelyi Mountains and the Balaton-Highland. (Here, like in the sequel, the term karstwater is used for groundwater in...

The determination of toxicokinetic parameters is an essential component in the risk assessment of potential harmful chemicals. It’s a first step to analyse the processes which are involved in the development of DNA adducts and might therefore lead to the development of cancer. The complete...

Research concerning the quantitative trait loci (QTL) mapping in plant genetics usually consists of two stages. The first stage is concerned with collecting data while the second one, based on the data collected, is concerned with a proper QTL study. The final inferences are strictly connected...

The determination of toxicokinetic parameters is an essential component in the risk assessment of potential harmful chemicals. It’s a first step to analyse the processes which are involved in the development of DNA adducts and might therefore lead to the development of cancer. The complete...

This paper presents the application of special unsupervised neural networks (self-organizing maps) to different domains, as sleep apnea discovery, protein sequences analysis and tumor classification. An enhancement of the original algorithm, as well as the introduction of several hierachical...

In this paper, hidden Markov models (HMMs) are discussed in the context of molecular biological sequence analysis. The statistics relevant in the HMM approach are described in detail. An HMM based method is used to analyze two proteins that contain short protein repeats (SPRs). As a benchmark, a...