Research concerning the quantitative trait loci (QTL) mapping in plant genetics usually consists of two stages. The first stage is concerned with collecting data while the second one, based on the data collected, is concerned with a proper QTL study. The final inferences are strictly connected...

In this paper, hidden Markov models (HMMs) are discussed in the context of molecular biological sequence analysis. The statistics relevant in the HMM approach are described in detail. An HMM based method is used to analyze two proteins that contain short protein repeats (SPRs). As a benchmark, a...

This paper presents the application of special unsupervised neural networks (self-organizing maps) to different domains, as sleep apnea discovery, protein sequences analysis and tumor classification. An enhancement of the original algorithm, as well as the introduction of several hierachical...

In the present study we investigate the data provided by the karstwater level monitoring system set up in the Transdanubian Mountains, more precisely in the Bakony, the Keszthelyi Mountains and the Balaton-Highland. (Here, like in the sequel, the term karstwater is used for groundwater in...

This work, and specially, the use of clustering algorithms was motivated by the need to perform a field-study with erosion data from arid areas. Using data obtained from analyzing erosion, land degradation and desertification phenomena will show some limitations. If only terrestrial observations...

Evaluation of hazards associated with exposure to chemicals, understanding of relationships between dose and adverse effect, extrapolation of effects from high experimental doses to low doses associated with actual exposures, and extrapolation from effects observed in animals to effects expected...

The expanding availability of protein data enforces the application of empirical methods necessary to recognize protein structures. In this paper a sequence-structure alignment method is described and applied to various Ubiquitin-like folded Ras-binding domains. On the basis of two probability...

The protein family of septins is analyzed with the SOM methodology of Andrade et al. (1997) to determine the family relationships and the key residues responsible for the obtained classification. These key residues are candidates for determining functional sites of the proteins. The advantages...

The structural analysis of proteins is fundamental to the analysis of protein functions. In this context, sequence-structure alignment methods are important among the different empirical methods. In order to assess the quality of sequence-structure alignments, a statistical method using a...