Min, Yuan; Xin, Tian; Gang, Zheng; Yaning, Yang - In: Statistical Applications in Genetics and Molecular Biology 8 (2009) 1, pp. 1-20
The transmission disequilibrium test (TDT) is a standard method to detect association using family trio design. It is optimal for an additive genetic model. Other TDT-type tests optimal for recessive and dominant models have also been developed. Association tests using family data, including the...