Lu, Tao; Huang, Yangxin; Wang, Min; Qian, Feng - In: Journal of Applied Statistics 41 (2014) 8, pp. 1645-1657
HIV dynamic models, a set of ordinary differential equations (ODEs), have provided new understanding of the pathogenesis of HIV infection and the treatment effects of antiviral therapies. However, to estimate parameters for ODEs is very challenging due to the complexity of this nonlinear system....