A study or experiment can be described as sequential if its design includes one or more interim analyses at which it is possible to stop the study, having reached a definitive conclusion concerning the primary question of interest. The potential of the sequential study to terminate earlier than...

Previous research investigating sketching processes during object visualisation and design has indicated that drawing occurs in a primarily part-bypart manner, whereby the component volumetric structures of objects appear to dominate the organisation of ongoing activity. Some non-part-by-part...

Adaptive two-stage designs allow a data-driven change of design characteristics during the ongoing trial. One of the available options is an adaptive choice of the test statistic for the second stage of the trial based on the results of the interim analysis. Since there is often only a vague...

In der Stromversorgung vollzieht sich seit etwa zwanzig Jahren ein grundlegender Wandel von konventioneller Stromerzeugung durch hauptsächlich Kohle- und Atomkraftwerke hin zu erneuerbaren Stromerzeugung durch hauptsächlich Windkraft- und Solaranlagen. Die Hauptunterschiede zwischen diesen...

Background and objective: An economic analysis of telemedicine support to improve glycemic control in patients with type 2 diabetes mellitus, illustrating the use of an analytic framework that efficiently combines telemedicine program findings with published estimates of treatment cost...