National household and individual level data are used to explore perceived neighbourhood characteristics (PNC) and neighbourhood social participation (NSP) associations with later life disability onset (DO). The sample includes 3,011 older people, with 8,128 observations between 1995 and 2001....

Purpose: To describe the economic burden of cancer survivorship for disease-free breast, colorectal and prostate cancer patients in the UK, one year post-diagnosis. Methods: Patient-level data were collected over a three months period 12-15 months post diagnosis to estimate the monthly societal...

Background: Over four millions people in England are estimated to have a CVD and they are responsible for over one third of deaths and a fifth of hospital admissions in England every year. In prioritising the reduction of premature mortality there has been a focus on improving prevention and...

The increasingly explicit use of health technology assessment continues to generate substantial public and academic policy debates. The debates are about puzzling issues whose correct resolution is not immediately obvious and the very explicitness of HTA’s use pinpoints the issues and locates...

Aim: Pressure Ulcers are an important health care problem, recognized as ‘Never Events’ by the US Government. To date, there is no instrument to capture their health utility impact, or the value of treatments and prevention strategies. The Pressure Ulcer Quality of Life Utility Instrument...

Health care systems are increasingly under pressure to provide funding for innovative technologies. These technologies tend to be characterized by their potential to make valued contributions to patient health in areas of relative unmet need, high acquisition costs and great uncertainty in the...

Purpose: To provide insights on the relationship between health and employment in older age. Design/methodology: Qualitative methods are used with some additional quantitative analysis to explore generalisations. The qualitative analysis is based on interviews with 56 men and women between the...

The methodology used when estimating utilities assumes that the best health state in a health-related quality of life (HrQoL) measure is equivalent to perfect health, with both valued at one. In this paper we explore the impact of relaxing this assumption by treating measured utilities as...

Background: Trastuzumab has significantly improved survival outcomes for women with HER2 positive early breast cancer. Trastuzumab was established as a costeffective adjuvant treatment in 2006. We present an updated cost-effectiveness analysis from the UK perspective which explores assumptions...

Cost-utility analysis is used within the health technology assessment processes of many countries. For these analyses, patients typically indicate the health state that they are in based on a pre-defined descriptive classification. Each health state corresponds to a utility value; these values...