Showing 1 - 10 of 28
Some failure time data come from a population that consists of some subjects who are susceptible to and others who are nonsusceptible to the event of interest. The data typically have heavy censoring at the end of the follow-up period, and a standard survival analysis would not always be...
Persistent link: https://www.econbiz.de/10009476571
Cure models can be used for censored survival data in which a fraction of the observations do not exhibit the event of interest despite long-term follow-up. In this paper we investigate the identifiability of two forms of the cure model, a standard cure model based on a mixture distribution and...
Persistent link: https://www.econbiz.de/10005224168
We consider the situation of two ordered categorical variables and a binary outcome variable, where one or both of the categorical variables may have missing values. The goal is to estimate the probability of response of the outcome variable for each cell of the contingency table of categorical...
Persistent link: https://www.econbiz.de/10009476597
Cognition is not directly measurable. It is assessed using psychometric tests, which can be viewed as quantitative measures of cognition with error. The aim of this article is to propose a model to describe the evolution in continuous time of unobserved cognition in the elderly and assess the...
Persistent link: https://www.econbiz.de/10009476639
Cure models have been developed to analyze failure time data with a cured fraction. For such data, standard survival models are usually not appropriate because they do not account for the possibility of cure. Mixture cure models assume that the studied population is a mixture of susceptible...
Persistent link: https://www.econbiz.de/10009476807
We consider using observational data to estimate the effect of a treatment on disease recurrence, when the decision to initiate treatment is based on longitudinal factors associated with the risk of recurrence. The effect of salvage androgen deprivation therapy (SADT) on the risk of recurrence...
Persistent link: https://www.econbiz.de/10009476813
The weighted Kaplan–Meier (WKM) estimator is often used to incorporate prognostic covariates into survival analysis to improve efficiency and correct for potential bias. In this paper, we generalize the WKM estimator to handle a situation with multiple prognostic covariates and...
Persistent link: https://www.econbiz.de/10009476916
We compare and contrast several different methods for estimating the effect of treatment when responses are paired binomial observations. The ratio of binomial probabilities is the parameter of interest, while the binomial probabilities are nuisance parameters which may vary between pairs. The...
Persistent link: https://www.econbiz.de/10009477202
In this article we investigate regression calibration methods to jointly model longitudinal and survival data using a semiparametric longitudinal model and a proportional hazards model. In the longitudinal model, a biomarker is assumed to follow a semiparametric mixed model where covariate...
Persistent link: https://www.econbiz.de/10009477552
Persistent link: https://www.econbiz.de/10003676672