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Population toxicokinetics of ethylene: Calibration and preceding investigations
Quinke, Barbara; Selinski, Silvia; Golka, Klaus; … - 2000
present approach is part of a strategy to determine the processes of uptake, elimination, and metabolism of the gas ethylene …- and BAT-values. This paper deals with the calibration, which is indispensable to determine the decline of atmospheric … concentrations of ethylene within a broad range of initial concentrations applied in an inhalation experiment. …
Persistent link: https://www.econbiz.de/10010316648
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Population toxicokinetics of ethylene : calibration and preceding investigations
Quinke, B.; Selinski, S.; Golka, Klaus; Blaszkewicz, M. - 2000
present approach is part of a strategy to determine the processes of uptake, elimination, and metabolism of the gas ethylene …- and BAT-values. This paper deals with the calibration, which is indispensable to determine the decline of atmospheric … concentrations of ethylene within a broad range of initial concentrations applied in an inhalation experiment. …
Persistent link: https://www.econbiz.de/10009789901
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Interindividual and interoccasion variability of toxicokinetic parameters of uptake, exhalation, and metabolism of ethylene
Schirm, Florian A.; Selinski, Silvia - 2000
the results of an inhalation study with one of the basic petrochemical industrial compounds, ethylene (ethene). Two …
Persistent link: https://www.econbiz.de/10010316508
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Estimation of toxicokinetic population parameters in a four-stage hierarchical model
Selinski, Silvia - 2000
A basic part in the risk assessment of potential carcinogens is the determination of toxicokinetic parameters. The partition of the xenobiotic in the body of experimental animals is a first step of the biochemical pathway of the formation of DNA adducts which might lead to the development of...
Persistent link: https://www.econbiz.de/10010316653
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Interindividual and interoccasion variability of toxicokinetic parameters of uptake, exhalation, and metabolism of ethylene
Schirm, Florian A.; Selinski, Silvia - 2000
the results of an inhalation study with one of the basic petrochemical industrial compounds, ethylene (ethene). Two …
Persistent link: https://www.econbiz.de/10009787268
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Estimation of toxicokinetic population parameters in a four-stage hierarchical model
Selinski, Silvia - 2000
A basic part in the risk assessment of potential carcinogens is the determination of toxicokinetic parameters. The partition of the xenobiotic in the body of experimental animals is a first step of the biochemical pathway of the formation of DNA adducts which might lead to the development of...
Persistent link: https://www.econbiz.de/10009789899
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Estimation of toxicokinetic population parameters in a four-stage hierarchical model
Selinski, Silvia - Institut für Wirtschafts- und Sozialstatistik, … - 2000
A basic part in the risk assessment of potential carcinogens is the determination of toxicokinetic parameters. The partition of the xenobiotic in the body of experimental animals is a first step of the biochemical pathway of the formation of DNA adducts which might lead to the development of...
Persistent link: https://www.econbiz.de/10010955416
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Interindividual and interoccasion variability of toxicokinetic parameters of uptake, exhalation, and metabolism of ethylene
Schirm, Florian A.; Selinski, Silvia - Institut für Wirtschafts- und Sozialstatistik, … - 2000
the results of an inhalation study with one of the basic petrochemical industrial compounds, ethylene (ethene). Two …
Persistent link: https://www.econbiz.de/10010955473
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Population toxicokinetics of ethylene: Models and validation of first order assumptions on kinetic processes
Selinski, Silvia; Quinke, Barbara; Golka, Klaus; Bolt, … - 2002
basic petrochemical industrial compounds, ethylene 2 (ethene), which is also a physiological body constituent, to its … metabolite, ethylene oxide, which is a proven carcinogen. …
Persistent link: https://www.econbiz.de/10010316453
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Population toxicokinetics of ethylene : models and validation of first order assumptions on kinetic processes
Selinski, Silvia; Quinke, Barbara; Golka, Klaus; Bolt, … - 2002
basic petrochemical industrial compounds, ethylene 2 (ethene), which is also a physiological body constituent, to its … metabolite, ethylene oxide, which is a proven carcinogen. …
Persistent link: https://www.econbiz.de/10009770916