Positive estimators of the between-group (between-study) variance are proposed. Explicit variance formulae for the estimators are given and approximate confidence intervals for the between-group variance are constructed, as our proposal to a long outstanding problem. By Monte Carlo simulation,...

In this paper, we consider one-step outlier identification rules for multivariate data-generalizing the concept of so-called a - outlier identifiers_ as presented in Davies and Gather (1993) for the case of univariate samples. We investigate how the finite sample breakdown points of estimators...

The basic ideas of Desirability functions and indices are introduced and compared to other methods of multivariate optimisation. It is shown that gradient based techniques are not in general appropriate to perform the numerical optimisation for Desirability indices. The problems are shown for...

Clinical information systems can record numerous variables describing the patient’s state at high sampling frequencies. Intelligent alarm systems and suitable bedside decision support are needed to cope with this flood of information. A basic task here is the fast and correct detection of...

This paper introduces ideas and methods for testing for structural change in linear regression models and presents how these have been realized in an R package called strucchange. It features tests from the generalized uctuation test framework as well as from the F test (Chow test) framework....

In many fields of applications, test statistics are obtained by combining estimates from several experiments, studies or centres of a multicentre trial. The commonly used test procedure to judge the evidence of a common overall effect can result in a considerable overestimation of the...