In pharmacoeconomics, the comparison of the costs of 2 different drugs used for the same treatment is of great interest. The problem is especially challenging when the drugs are likely to produce costly adverse effects in a small number of patients, which is often the case. The data are then...

Let X ~ N([theta],1), where [theta] [epsilon] [-m, m], for some m 0, and consider the problem of estimating [theta] with quadratic loss. We show that the Bayes estimator [delta]m, corresponding to the uniform prior on [-m, m], dominates [delta]0 (x) = x on [-m, m] and it also dominates the MLE...

This article derives improved estimators of the dispersion parameter, [lambda], of an inverse Gaussian distribution by employing techniques similar to those of Brown (1968) and Brewster and Zidek (1974) in the normal variance problem.

Although sample size calculations for testing a parameter in the Poisson regression model have been previously done, very little attention has been given to the effect of the correlation structure of the explanatory covariates on the sample size. A method to calculate the sample size for the...