The multilevel Monte Carlo path simulation method introduced by Giles (Operations Research, 56(3):607-617, 2008) exploits strong convergence properties to improve the computational complexity by combining simulations with different levels of resolution. Previous research has analysed its...

A stochastic model for replicators in catalyzed RNA-like polymers is presented and numerically solved. The model consists of a system of reaction–diffusion equations describing the evolution of a population formed by RNA-like molecules with catalytic capabilities in a prebiotic process. The...

Vaccines against COVID-19 are under development. As a scarce resource, the health authorities have to decide how to prioritise the vaccine in the target population. The aim of this paper is to explore the cost-effectiveness of a COVID-19 vaccine and to analyse how the vaccine price, and the cost...