Thiazolidinedione (TZD) drugs (Takeda Pharmaceuticals and Metabolic Solutions Development Company) targeting inhibition of the mitochondrial pyruvate carrier (MPC) are currently being tested in clinical trials to prevent progression into mild cognitive impairment of Alzheimer's disease (AD) or...

Deposition of α–synuclein, tau and β–amyloid protein plaques in brain leads to neurodegeneration. A series of indolin derivatives, which can bind to α–synuclein and detect Parkinson's disease (PD), were used for development of QSAR and QAAR models. It is the first attempt of QSAR for...

This paper mainly discusses the use of mutual information (MI) and Support Vector Machines (SVMs) for Uyghur Web text classification and digital forensics process of web text categorization: automatic classification and identification, conversion and pretreatment of plain text based on encoding...

Building classification models from real-world datasets became a difficult task, especially in datasets with high dimensional features. Unfortunately, these datasets may include irrelevant or redundant features which have a negative effect on the classification performance. Selecting the...

A novel hybrid method based on Cosine Similarity and Mutual Information is presented to find out relevant feature subset. Initially, the supervised Cosine Similarity of each feature is calculated with respect to the class vector and then features are grouped based on the obtained cosine...

According to different typologies of activity and priority, risks can assume diverse meanings and it can be assessed in different ways. In general risk is measured in terms of a probability combination of an event (frequency) and its consequence (impact). To estimate the frequency and the impact...

The paper formalizes Warner's (1965) randomized response technique (RRT) as a game and implements it experimentally, thus linking game theoretic approaches to randomness in communication with survey practice in the field and a novel implementation in the lab. As predicted by our model and in...

Analyzing social systems, particularly financial markets, using a complex network approach has become one of the most popular fields within econophysics. A similar trend is currently appearing within the econometrics and finance communities, as well. In this study, we present a...

Research papers that studied the Triple Helix in relation to international co-authorship considered international collaboration as the fourth element of the system. This paper suggests considering three levels of study to assess the effect of international collaboration on an innovation system:...