Process modeling has gained prominence in the information systems modeling area due to its focus on business processes and its usefulness in such business improvement methodologies as Total Quality Management, Business Process Reengineering, and Workflow Management. However, process modeling...

A method is presented for automated preparation of bootstrap data samples and their presentation to NONMEM for use in the validation of population pharmacokinetic or pharmacodynamic models, which have been developed with relatively small numbers of subjects. The bootstrap sampling procedure...

Enterprise systems interoperability (ESI) is an important topic for business currently. This situation is evidenced, at least in part, by the number and extent of potential candidate protocols for such process interoperation, viz., ebXML, BPML, BPEL, and WSCI. Wide-ranging support for each of...

This study was conducted to develop a method, termed 'back analysis (BA)', for converting non-compartmental variables to compartment model dependent pharmacokinetic parameters for both one- and two-compartment models. A Microsoft Excel((R)) spreadsheet was implemented with the use of Solver((R))...

Much research has been devoted over the years to investigating and advancing the techniques and tools used by analysts when they model. As opposed to what academics, software providers and their resellers promote as should be happening, the aim of this research was to determine whether...

In an environment where privacy is an increasing concern to users that communicate through a public network, anonymity systems can play a fundamental role in helping safeguard users' identities. The peer-to-peer (P2P) architecture has emerged as a promising paradigm for designing large-scale...

Many applications require predicting not a just a single variable, but multiple variables that depend on each other. Recent attention has therefore focused on structured prediction methods, which combine the modeling flexibility of graphical models with the ability to employ complex, dependent...

Local area networks (LANs) provide links between computing devices, such as workstations, file servers, and printers, over a relatively small geographic area (usually within a single building or organization). While computer networks have existed for almost thirty years, networking technology...

Program dependences are syntactic relationships between program statements, which are used in several areas of computer science to obtain "approximate" information about semantic relationships between statements. There are two basic types of program dependences: control dependences, which are...

This study examines the design and development of computer-aided composition (CAC) software and its implications for Composition in general. The aims of the study were to identify the who and how of CAC software design and possibly construct models for CAC software development. In addition, the...