Merging data from multiple studies has been widely adopted in biomedical research. In this paper, we consider two major issues related to merging longitudinal datasets. We first develop a rigorous hypothesis testing procedure to assess the validity of data merging, and then propose a flexible...

In some commonly used longitudinal clinical trials designs, the quadratic inference functions (QIF) method fails to work due to non-invertible estimation of the optimal weighting matrix. We propose a modified QIF method, in which the optimal weighting matrix is estimated by a linear shrinkage...

This paper concerns goodness-of-fit test for semiparametric copula models. Our contribution is two-fold: we first propose a new test constructed via the comparison between "in-sample" and "out-of-sample" pseudolikelihoods, which avoids the use of any probability integral transformations. Under...

In this article, we focus on the circumstances in quasi-likelihood inference that the estimation accuracy of mean structure parameters is guaranteed by correct specification of the first moment, but the estimation efficiency could be diminished due to misspecification of the second moment. We...

This paper concerns goodness-of-fit test for semiparametric copula models. Our contribution is two-fold: we first propose a new test constructed via the comparison between "in-sample" and "out-of-sample" pseudolikelihoods, which avoids the use of any probability integral transformations. Under...

We propose a new class of state space models for longitudinal discrete response data where the observation equation is specified in an additive form involving both deterministic and random linear predictors. These models allow us to explicitly address the effects of trend, seasonal or other...