Amid the prolonged COVID-19 pandemic, the miraculous breakthroughs of multiple effective and safe COVID-19 vaccines offer hopeful prospects. Yet, the endgame of the pandemic is not vaccines; it is vaccination. The daunting challenge of vaccinating the world offers ample investigative...

Every year, nearly 5,000 patients die while waiting for kidney transplants, and yet an estimated 3,500 procured kidneys are discarded. Such a polarized co-existence of dire scarcity and massive wastefulness has been mainly driven by insufficient pooling of cadaveric kidneys across geographic...

Distributing scarce resources such as COVID-19 vaccines is often a highly time-sensitive and mission-critical operation. On top of that, most COVID-19 vaccines require two doses to be administered three or four weeks apart. How to effectively roll out two-dose vaccines is a crucial policy...

The ongoing discourse about COVID-19 testing revolves around undertesting (i.e., insufficient testing capacity relative to demand). An important yet little studied systematic issue is overdiagnosis (i.e., positive diagnoses for patients with negligible viral loads): recent evidence shows U.S....

Problem Definition: Among the most vexing issues in the U.S. healthcare ecosystem is inappropriate usage of percutaneous coronary intervention (PCI) procedures, also known as “overstenting.” A key driver of overstenting is physician subjectivity in “eyeballing” a coronary angiogram....

Cardiovascular diseases (CVDs) are the leading cause of death and disability both in the United States and worldwide. Despite high morbidity, mortality, and cost in the US and global healthcare systems, cardiovascular care has been under-studied in the healthcare operations management...

Manufacturing and supply networks worldwide are undergoing digital transformation under the umbrella of Smart Manufacturing and Industry 4.0. Just as companies embrace digital technologies and leverage the opportunities presented by Artificial Intelligence (AI) forming digital supply networks,...

Health policymakers across the U.S. and around the globe have explored a Netflix-like subscription model for prescription drugs crucial for public health. Under this “Netflix model,” a government entity agrees to pay a fixed subscription fee to a pharmaceutical manufacturer for an unlimited...

A key challenge in the emerging field of precision nutrition entails providing diet recommendations that reflect both the (often unknown) dietary preferences of different patient groups and known dietary constraints specified by human experts. Motivated by this challenge, we develop a...

Motivated by a collaborative study with one of the most comprehensive ocular imaging programs in the United States, we investigate the underlying three-way tradeoffs among operational, clinic, and financial considerations in physicians’ decisions about ordering imaging tests. Laboratory tests...