overall QOL should be defined and measured in children. It is recommended that future studies focus on operationalising and … are still used interchangeably when comparing child and parent reports of children's HR-QOL. The Pearson correlation is a … may have occurred in the evaluation of HR-QOL. Most studies have compared HR-QOL scores of children with illness with …

Differences between children and adults have both technical and ethical implications for the design, interpretation and … and effectiveness of healthcare interventions; challenges in assessing utilities for infants and young children given … the rights and interests of children who cannot advocate for themselves. …

available on the overall occurrence of influenza in children, less information is available on the differential impact of … influenza on healthcare for previously healthy children and those at high risk of developing influenza-related complications …. Objective: To compare the frequency of influenza-related complications in healthy and `at-risk' children, and quantify the …

The health-related quality of life (HR-QOL) of children and adolescents is increasingly considered a relevant topic for … research. Instruments to assess quality of life in children and adolescents of a generic as well as disease- or condition …. This paper attempts to give an overview on the state of the art of HR-QOL assessment in children as it relates to …

(HR-QOL) in paediatric populations. Considerations specific to the evaluation of HR-QOL in children include children … problems and simply the fact that children are continually changing. We provide a review of the currently available literature …

children under 5 years of age. Vaccines which can prevent this infection are available. Objective: To evaluate the costs and … and participants: A cost-benefit analysis based on a birth cohort of 100 000 children. The state of health of the cohort … vaccination programme given at ages 2, 3 and 4 months. Results: The model predicted that vaccinating children against Hib …