Trastuzumab (TR), a monoclonal antibody approved by EMA in 2000 and one of the first examples of “targeted therapy”, is indicated to treat human epidermal growth factor receptor 2 (HER2) positive breast cancer. TR, whose patent will expire in 2015 in Europe, has been judged positively for...

The debate about future climate policy involves the question about the contribution of agriculture in meeting overall greenhouse gas mitigation targets. From an economic perspective, this calls for assessing and equalizing marginal mitigation costs across different sectors. To this end, we...

Randomised controlled trials (RCTs) are a major source of individual patient level data (IPD) on the clinical outcomes, costs and other measures of health consequences associated with alternative healthcare interventions. These data are typically used to establish the ‘value for...

Theoretical approaches to the assessment of natural resources have been substantiated. Existing approaches to the determination of the economic assessment methods have been generalized. The need to develop a common methodological approach to social, environmental and economic assessment of the...

Nach dem Verbot der konventionellen Käfighaltung in Deutschland stellte sich die Frage nach der Wirtschaftlichkeit von artgerechten alternativen Haltungssystemen. Über die Kleingruppenhaltung, welche relativ neu ist und wieder zur Debatte steht, liegen kaum praxisnahe Informationen vor. Diese...

With the interstate system substantially complete, the majority of new investment in highways is likely to take the form of selective capacity expansion projects in urban areas, along with incremental expansions and upgrades to expressway or freeway standards of existing intercity highway...

Despite widespread growth in on-road public transport priority schemes, road management authorities have few tools to evaluate the impacts of these schemes on all road users. This paper describes a methodology developed in Melbourne, Australia to assist the road management authority, VicRoads,...

Аграрное производство России на современном этапе является весьма энергоёмким. В себестоимости производства сельскохозяйственной продукции общая стоимость...

The objective of this study is to summarize the current general evaluation process that stakeholders use to evaluate single or multiple medical devices to select the optimal medical device. This study constructed a novel evaluation framework to select the optimal medical device by overcoming the...