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A comparison of robust methods for Mendelian randomization using multiple genetic variants
Bao, Yanchun; Clarke, Paul; Smart, Melissa C; Kumari, Meena - 2018
valid instrumental variable estimator" (sisVIVE) developed by Kang et al. (2016). We conduct a comprehensive simulation … study to assess sisVIVE for Understanding Society-like data, and find that it outperforms alternative methods across a range … because the consistency criterion for sisVIVE does not identify the true causal effect if InSIDE fails. In the application to …
Persistent link: https://www.econbiz.de/10011867491
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Instrumental Variable Estimation with the R Package ivtools
Sjolander, Arvid; Martinussen, Torben - In: Epidemiologic Methods 8 (2019) 1
Abstract Instrumental variables is a popular method in epidemiology and related fields, to estimate causal effects in the presence of unmeasured confounding. Traditionally, instrumental variable analyses have been confined to linear models, in which the causal parameter of interest is typically...
Persistent link: https://www.econbiz.de/10014590645
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Predicting the Direction of Causal Effect Based on an Instrumental Variable Analysis: A Cautionary Tale
Burgess, Stephen; Small, Dylan S. - In: Journal of Causal Inference 4 (2016) 1, pp. 49-59
Abstract An instrumental variable can be used to test the causal null hypothesis that an exposure has no causal effect on the outcome, by assessing the association between the instrumental variable and the outcome. Under additional assumptions, an instrumental variable can be used to estimate...
Persistent link: https://www.econbiz.de/10014610833
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Mendelian randomization: Estimation of inpatient hospital costs attributable to obesity
Dick, Katherine; Schneider, John E.; Briggs, Andrew Harvey - In: Health Economics Review 11 (2021) 1, pp. 1-12
Background: Mendelian Randomization is a type of instrumental variable (IV) analysis that uses inherited genetic variants as instruments to estimate causal effects attributable to genetic factors. This study aims to estimate the impact of obesity on annual inpatient healthcare costs in the UK...
Persistent link: https://www.econbiz.de/10014489877
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Genetic markers as instrumental variables: An application to child fat mass and academic achievement
von Hinke Kessler Scholder, Stephanie; Smith, George Davey - 2010
The use of genetic markers as instrumental variables (IV) is receiving increasing attention from economists. This paper examines the conditions that need to be met for genetic variants to be used as instruments. We combine the IV literature with that from genetic epidemiology, with an...
Persistent link: https://www.econbiz.de/10010288210
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Child height, health and human capital : evidence using genetic markets
Hinke Kessler Scholder, Stephanie von; Smith, George Davey - In: European economic review : EER 57 (2013) 1, pp. 1-22
Persistent link: https://www.econbiz.de/10009706230
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Mendelian randomization : estimation of inpatient hospital costs attributable to obesity
Dick, Katherine; Schneider, John E.; Briggs, Andrew Harvey - In: Health economics review 11 (2021) 1, pp. 1-12
Background: Mendelian Randomization is a type of instrumental variable (IV) analysis that uses inherited genetic variants as instruments to estimate causal effects attributable to genetic factors. This study aims to estimate the impact of obesity on annual inpatient healthcare costs in the UK...
Persistent link: https://www.econbiz.de/10012544740
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Mendelian randomization analysis of the causal effect of adiposity on hospital costs
Dixon, Padraig; Hollingworth, William; Harrison, Sean; … - In: Journal of health economics 70 (2020), pp. 1-22
Persistent link: https://www.econbiz.de/10012493964
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Genetic markers as instrumental variables
Hinke Kessler Scholder, Stephanie von; Smith, George Davey - In: Journal of health economics 45 (2016), pp. 131-148
Persistent link: https://www.econbiz.de/10011579994
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Genetic Markers as Instrumental Variables
Scholder, Stephanie von Hinke Kessler; Smith, George Davey - Centre for Market and Public Organisation (CMPO), … - 2011
The use of genetic markers as instrumental variables (IV) is receiving increasing attention from epidemiologists, economists, statisticians and social scientists. This paper examines the conditions that need to be met for genetic variants to be used as instruments. Although these have been...
Persistent link: https://www.econbiz.de/10009370149