bottom-up approach the direct costs of these patients yielding per patient costs of 23,297 euros on average. Linking the … direct costs per patient with the incidence data, the total direct costs for severe sepsis in Germany per year were estimated … to range from 1,025 to 2,214 million euros. Direct costs, however, were found to make up only about 28% of the burden of …

intangible costs. The aim of this paper is to critically describe the different methods for estimating each of these costs. The … valuation of the costs of an illness involves a vector of prices and quantities. The quantities arise from the resources used or …

Taiwan). The COI was calculated by summing the direct costs, morbidity costs, and mortality costs. We compared the COIs of …