Joo, Yongsung; Casella, George; Booth, James; Lee, Keunbaik - In: Statistical Applications in Genetics and Molecular Biology 6 (2007) 1, pp. 2-2
This paper discusses characteristics of dye biases in microarray data that the conventional normalization methods do not handle, and proposes a new normalization method involving a mixture of splines model. We also develop a test for between-group comparisons of each gene that is designed to be...